If you are going on a long trip make sure your teeth are okay. If you have spectacles it would be a good idea to take a pair of spare glasses. If you are on medication, take a good supply of all your medicines as these might be unavailable in Nepal. In order to make replacements easier make sure you take the generic name rather than the brand name of the medicine. It might be a good idea to take a prescription or letter from your doctor to show that you are on medication.